Fig. 5From: Inferring the number and position of changes in selective regime in a non-equilibrium mutation-selection frameworkIdentification of selective shifts on an empirical \(\beta \)-lactamase phylogeny [49]. Shown is a diversified sample of the phylogeny constructed by removing the shallowest divergences from the original study [49]. Coloured circles mark out the position of inferred selective shifts. For reference, black circles mark out the lineage shown to have undergone a functional change in the original study. PNCA Common ancestor of various Gram-positive and Gram-negative bacteria; ENCA Common ancestor of EnterobacteriaBack to article page