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Table 1 Defects in F1 embryos derived from crossing wild type males to F0 females that had been injected with npm2a or npm2b CRISPR mRNA as embryos

From: Double maternal-effect: duplicated nucleoplasmin 2 genes, npm2a and npm2b, with essential but distinct functions are shared by fish and tetrapods

Penetrance of npm2a and npm2b mutant phenotypes
  Total number of embryos Embryos with defects
Non-cellularized Partially cellularized Normal embryos % Abnormal embryos
npm2a-1 741 366 0 375 49%
npm2a-2 252 237 0 15 94%
npm2a-3 107 82 0 25 77%
npm2a-4 150 147 0 3 98%
npm2b-1 105 47 42 16 85%
npm2b-2 66 60 6 0 100%
npm2b-3 263 129 134 0 100%
npm2b-4 525 347 173 5 99%
npm2b-5 376 100 92 184 51%
  1. npm2a nucleoplasmin 2a, npm2b nucleoplasmin 2b
  2. This table demonstrates representative data from a single clutch from each mutant female. Embryos did not develop at all (please refer to Fig. 7e-l). Embryos had a partially cellularized blastodisc that was sitting atop an enlarged yolk syncytial layer (please refer to arrows in Fig. 7n and o)