Skip to main content

Advertisement

Table 4 Candidate transcripts upregulated in hybrids compared to X. muelleri.

From: Gene expression analysis of the ovary of hybrid females of Xenopus laevis and X. muelleri

ProbeID GenBank ID Target Gene GeneSymbol Description/Molecular Function Mean Muell. SD Muell. Mean Hybrid SD Hybrid M-H P value
Xl.4276.1.S1_at X53745.1 Cyclin A1 LOC397885 Regulation of progression through cell cycle 5.12 0.58 12.76 0.10 -7.64 0.0001
Xl.8319.1.S1_at BJ098891 Herz03 Herz03   4.84 0.22 11.65 0.03 -6.80 0.0001
Xl.21809.1.S1_at BC041555.1 MGC53900 MGC53900 Similar to calcium modulating ligand 3.00 0.31 9.78 0.23 -6.79 0.0001
Xl.17345.1.A1_at BJ053357 EST MGC115708 Weakly similar to MIC2_HUMAN T-cell surface glycoprotein E2 precursor (H. sapiens) 3.33 0.21 10.03 0.99 -6.70 0.0002
Xl.4744.1.S1_at BE491637   LOC495025 Moderately similar to ubiquitin thiolesterase (H. sapiens); ubiquitin-dependent protein catabolism 4.78 0.60 11.43 0.16 -6.65 0.0002
Xl.6585.1.S1_at BJ080015 Similar to HIV-1 rev binding protein 2 HRB2 RNA binding 3.22 0.20 9.75 0.14 -6.53 0.0001
Xl.21357.2.S1_at BJ045324 Claudin7L1 MGC53400 Xenopus laevis cldn7L1 mRNA for Claudin7L1, structural molecule activity 3.90 0.27 10.42 0.03 -6.51 0.0001
Xl.14775.1.A1_at BM179359 EST   Weakly similar to POL2_MOUSE Retrovirus-related POL polyprotein (M. musculus) 3.81 0.18 10.23 0.22 -6.43 0.0001
Xl.3668.1.S1_at AF450296.1 XLCL2 LOC397879 Xenopus laevis F-box protein (PXP17), meiosis 4.46 0.60 10.82 0.06 -6.36 0.0002
Xl.3401.2.A2_at BG016692 EST LOC446970 Similar to axotrophin; likely ortholog of mouse axotrophin (H. sapiens), protein binding 3.72 0.63 9.95 0.14 -6.24 0.0002
Xl.1018.1.A1_at U44950.1 Vitelline envelope glycoprotein lzpb-a Xenopus laevis vitelline envelope 37 k glycoprotein xlZPB 4.10 0.53 10.31 0.29 -6.22 0.0002
Xl.3862.2.S1_x_at CD361360 Translation factor sui1 gc20 Translation initiation factor activity 3.29 0.41 9.45 0.17 -6.16 0.0001
Xl.7151.1.S1_at BJ089477 EST MGC68561 Moderately similar to hypothetical protein FLJ10738 (H. sapiens); 3'-5' exonuclease activity 4.69 0.31 10.84 0.21 -6.15 0.0001
Xl.3536.2.S1_x_at BF615663 EST LOC495200 Highly similar to transcription factor BTF3a – (H. sapiens) 4.19 0.26 10.32 1.21 -6.13 0.0004
Xl.23448.1.S1_at BC041216.1 SWI/SNF smarce1 Similar to SWISNF, actin dependent regulator of chromatin, regulation of transcription 3.75 0.62 9.88 0.23 -6.13 0.0002
Xl.2060.1.A1_x_at BJ055271 EST    3.61 0.40 9.69 1.64 -6.08 0.0008
Xl.576.1.S1_at AF184090.1 fatvg fatvg   4.94 0.56 11.02 0.03 -6.08 0.0002
Xl.24785.1.S1_at BM261081 EST MGC81067   4.41 0.07 10.41 0.03 -5.99 0.0001
Xl.4504.1.A1_at BJ076394 EST   Weakly similar to ACRC protein; putative nuclear protein (H. sapiens) 4.11 1.10 10.10 0.06 -5.99 0.0007
Xl.7045.1.S1_a_at BQ398421 EST   Weakly similar to CTF1_HUMAN Cardiotrophin-1 (CT-1) (H. sapiens) 2.67 0.16 8.64 0.24 -5.97 0.0001
Xl.7252.1.S1_at AY172320.1 Germes LOC398520   3.60 0.18 9.55 0.27 -5.96 0.0001
Xl.2565.3.S1_x_at CB561588 Similar to alpha-Tubulin at 84B MGC53359 Xenopus laevis, Similar to alpha-Tubulin at 84B, microtubule-based movement 4.44 0.41 10.39 0.27 -5.95 0.0002
Xl.7837.1.A1_at BF232270 EST MGC132211 Highly similar to hypothetical protein FLJ10900 (H. sapiens), electron transport 2.94 0.43 8.88 0.02 -5.94 0.0001
Xl.25809.1.A1_at BE026874 EST MGC80281 Histidine catabolism 4.26 0.49 10.18 0.36 -5.92 0.0002
Xl.6605.1.A1_at AW632842 EST    3.59 0.26 9.50 0.02 -5.91 0.0001
Xl.4170.2.A1_at BQ398301 LOC494857 LOC494857 Cell differentiation 4.21 0.59 10.11 0.11 -5.90 0.0002
Xl.1014.1.S1_at U46131.1 Cdc21 protein cdc21 Xenopus laevis DNA replication initiator protein, DNA replication initiation, regulation of transcription 4.14 0.46 10.00 0.08 -5.86 0.0002
Xl.2839.1.S1_at BC041270.1 Protein translocation complex sec61beta Similar to protein translocation complex beta 5.91 0.17 11.76 0.08 -5.85 0.0001
Xl.25536.1.A1_at BE677987 EST   Weakly similar to hypothetical protein MGC2577 (H. sapiens) 4.36 1.14 10.15 0.93 -5.79 0.0012
Xl.14065.1.A1_at AW147826 EST    3.61 0.15 9.33 0.12 -5.72 0.0001
  1. Top 30 candidate transcripts upregulated in hybrids and differentially expressed between females of X. muelleri and hybrids. Expression values are in log2 scale; SD = standard deviation of expression values. P values are adjusted according to FDR moderated t-tests.