From: Directional and balancing selection in human beta-defensins
Gene | Human – macaque non-synonymous fixed changes | Human – macaque synonymous fixed changes | Human non-synonymous polymorphisms | Human synonymous polymorphisms | Rs number | Human non-synonymous polymorphic sites | Indigenous Australians | UK population | Other sub-saharan Africans | Mbuti/Biaka | Agriculturalists | Hunter-Gatherers | Fisher's exact test p value (not corrected for multiple tests) | African | Non-African | Fisher's exact test p value (not corrected for multiple tests) |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DEFB127 | 8 | 6 | 4 | 1 | 16995685 | R71S | 4 | 8 | 0 | 1 | 8 | 5 | 0.175 | 1 | 12 | 0.002 |
 |  |  |  |  | - | R71H | 0 | 0 | 0 | 2 | 0 | 2 | 0.288 | 2 | 0 | 0.208 |
 |  |  |  |  | 12624954 | G31R | 4 | 8 | 0 | 1 | 8 | 5 | 0.175 | 1 | 12 | 0.002 |
 |  |  |  |  | - | K58R | 0 | 0 | 1 | 0 | 1 | 0 | 0.459 | 1 | 0 | 0.459 |
DEFB120 | 13 | 2 | 3 | 0 | - | H28R | 0 | 0 | 1 | 3 | 1 | 3 | 0.371 | 4 | 0 | 0.040 |
 |  |  |  |  | - | R46C | 1 | 0 | 0 | 0 | 0 | 1 | 0.541 | 0 | 1 | 0.541 |
 |  |  |  |  | - | *89EL* | 0 | 0 | 1 | 3 | 1 | 3 | 0.371 | 4 | 0 | 0.040 |
DEFB132 | 12 | 8 | 5 | 2 | - | W41S | 0 | 0 | 1 | 2 | 1 | 2 | 0.561 | 3 | 0 | 0.092 |
 |  |  |  |  | - | P63Q | 0 | 0 | 3 | 1 | 3 | 1 | 0.248 | 4 | 0 | 0.040 |
 |  |  |  |  | - | L70F | 0 | 0 | 1 | 2 | 1 | 2 | 0.561 | 0 | 3 | 0.152 |
 |  |  |  |  | - | V93I/T | 4 | 0 | 0 | 2 | 0 | 6 | 0.021 | 2 | 4 | 0.418 |
 |  |  |  |  | - | V93A/T | 3 | 0 | 1 | 9 | 1 | 12 | 0.002 | 10 | 3 | 0.015 |
DEFB118 | 11 | 7 | 2 | 0 | - | C34R | 0 | 1 | 0 | 0 | 1 | 0 | 0.459 | 0 | 1 | 0.541 |
 |  |  |  |  | - | I56V | 0 | 0 | 1 | 4 | 1 | 4 | 0.234 | 5 | 0 | 0.017 |
DEFB1 | 6 | 7 | 2 | 1 | - | F24C | 0 | 0 | 0 | 1 | 0 | 1 | 0.541 | 1 | 0 | 0.459 |
 |  |  |  |  | 2738047 | V38I | 0 | 0 | 0 | 1 | 0 | 1 | 0.541 | 1 | 0 | 0.459 |
n | 50 | 30 | 16 | 4 | - | 16 | 20 | 20 | 14 | 20 | 34 | 40 | - | 34 | 40 | - |