Different alternative splicing patterns are subject to opposite selection pressure for protein reading frame preservation

Table 1 The retrieved human-mouse orthologous exon pairs

Human-mouse ortholog Exon types		No. of human-mouse orthologous exon pairs
Group A: ASE conservation unspecified group
Human	Mouse
Simple ASEs	All exons	1,960
Complex ASEs	All exons	311
All exons	Simple ASEs	1,299
All exons	Complex ASEs	293
Group B: Lineage-specific ASE group
Human	Mouse
Simple ASEs	CSEs	1,635
Complex ASEs	CSEs	276
CSEs	Simple ASEs	932
CSEs	Complex ASEs	254
Group C: Conserved ASE group
Human	Mouse
Simple ASEs	All ASEs	325
Complex ASEs	All ASEs	35
All ASEs	Simple ASEs	367
All ASEs	Complex ASEs	39

Note: All exons include CSEs and all ASEs. All ASEs include simple ASEs, complex ASEs, and ASE type uncertain. Lineage-specific and conserved ASE groups are subsets of the ASE conservation unspecified group.

ISSN: 2730-7182