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Figure 1 | BMC Evolutionary Biology

Figure 1

From: Subfunctionalization of duplicated genes as a transition state to neofunctionalization

Figure 1

Eight different fates are possible in the two simulations, nonfunctionalization (pseduogenization) without cellular death, subfunctionalization, pleiotropic neofunctionalization plus either nonfunctionalization of the other copy or subfunctionalization, non-pleiotropic neofunctionalization, non-pleiotropic neofunctionalization also involving subfunctionalization, redundancy, and cellular death. Some of the fates have additional combinations of activity that are not represented in this figure. It should also be noted that some of the characterizations overlap. For example, pleiotropic neofunctionalization occurs in combination with nonfunctionalization, subfunctionalization, or is redundant.

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