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Table 1 Correlation between the number of protein-protein interactions and the evolutionary rate

From: No simple dependence between protein evolution rate and the number of protein-protein interactions: only the most prolific interactors tend to evolve slowly

Data set

Linear correlation coefficient (r)/ P-value

Rank correlation coefficient (R)/P-value

S. cerevisiae – S. pombe (all orthologs, N = 1044)

-0.081/0.009

-0.029/0.352

S. cerevisiae – S. pombe (only orthologs with >40% identity, N = 465)

-0.018/0.697

0.074/0.111

H. pylori J99 – H. pylori 26695 (N = 672)

-0.039/0.310

0.020/0.610

H. pylori – C. jejuni (N = 458)

-0.013/0.787

0.015/0.747