Figure 7
Cytotoxic effects of ConI, ConII, and Con-anc mutants on Jurkat cells. Solid square and continuous line represent ConI; solid circle and continuous line represent ConII; solid triangle and continuous line indicate Con-anc; hollow circle and dotted line indicate Con-anc-N/C/L5/L6; and hollow diamond and broken line represent Con-anc-N/C/L5/L6-T38 M. The calculated ED50 values (50% effective dose) were as follows: ConI, 0.098; ConII, 0.27; Con-anc, 1.2; Con-anc-N/C/L5/L6, 0.12; and Con-anc-N/C/L5/L6/L3, 0.11.