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Fig. 11 | BMC Evolutionary Biology

Fig. 11

From: Evolutionary diversity and novelty of DNA repair genes in asexual Bdelloid rotifers

Fig. 11

Ohnologs of Polλ. a Domain structure of the three types of polymerase λ in A. vaga. Boundaries of domains defined by hmmscan of PfamA are shown above (start) and below (end); the disordered Ser/Pro-rich region (SP) is not a defined domain. The three residues that make up the phosphate binding pocket in the 8kD domain are shown (RRK or RSK). The position of residues encoded by codons determined to be under positive selection in the lineage leading to AvPolA are shown above the A. vaga A structure clustered by diamonds for each domain. b Secondary structure of the BRCT domain in polymerase λ as determined by Phyre. Beta sheets are shown as blue arrows, alpha helices as pink cylinders. The region identified as the Pfam domain BRCT_2 by hmmscan is shown with domain-specific expectation value; positions of structure boundaries outside of the predicted BRCT domain are indicated. c Alignment of the disordered SP region in A. vaga copies of polymerase λ. Numbering is to AvPolLA1. Serine and proline residues are highlighted in blue and yellow, respectively. d Unrooted gene tree of the six copies of Pol λ in A. vaga and three additional rotifer species used for codeml tests of selection. 1, Seison sp.; 2, Brachionus manjavacas; 3, Brachionus calyciflorus. e Differential expression of the three paralogs entering and recovering from desiccation, compared to hydrated controls. Values are log2 fold change of normalized counts, significance test values are listed in Additional file 1

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