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Table 1 Analysis of known typically highly conserved key residues and amino acid motifs

From: The crowns have eyes: multiple opsins found in the eyes of the crown-of-thorns starfish Acanthaster planci

A. planci Opsin

Disulfide bonda (C110/C187)

LxxxDb (79)

Counterionc (E113/E181)

Schiff based (K296)

NPxxY(302)

C-opsin 1.1a (gbr.65.47.t1)

C/C

ICVAD

Y/E

K

NPVIY

C-opsin 1.1b (gbr.508.2.t1)

C/C

VCVAD

Y/−

K

NPVIY

C-opsin 1.2 (gbr.65.46.t1)

C/F

ISVGD

Y/−

R

N----

C-opsin 1.3 (gbr.65.45.t1)

L/C

VCEA-

Y/A

K

NPIIY

Go-opsin (gbr.470.6.t1)

C/C

MAVSD

I/E

K

NPLIY

R-opsin (gbr.176.5.t1)

C/C

LAFSD

Y/E

K

NPLVY

Chaopsin (gbr.176.10.t1)

C/C

LSGSD

Y/E

K

NPIIY

Peropsin (gbr.31.87.t1)

C/C

ASAGD

Y/E

K

NPLMF

RGR opsin (gbr.37.113.t1)

C/C

LCAGD

Y/E

K

NAALQ

Neuropsin (gbr.37.57.t1)

C/C

LAVSD

Y/E

K

NPIIY

  1. aMotif required for recognition of rhodopsin by G-protein [87]
  2. bMotif interacting with NPxxY motif upon receptor activation for structural constraints [88]
  3. cGlutamic acid residues stabilizing the Schiff base bond
  4. dLysine residue forming Shiff base bond with retinal Motif providing structural constraints in response to photoisomerization during formation of the G protein-activating Meta II [89]