Skip to main content
Fig. 3 | BMC Evolutionary Biology

Fig. 3

From: Detecting consistent patterns of directional adaptation using differential selection codon models

Fig. 3

Global and differential selection profiles (for HLA-B57). (a) Global selection profile (G). (b) Differential selection profile contrasting between- and within-patient selection. (c) Differential selection profile for HLA-B57+ versus HLA-B57-. The posterior probability (pp) of an increased fitness for N and a decreased fitness for T at position 242 (TW10 epitope), in HLA-B57+ compared to HLA-B57-, is 0.93 and 0.87, respectively. At position 163 (KF11 epitope), the fitness of N is increased with a pp. of 0.77. The logos are filtered for pp. below 0.05. Heights are proportional to posterior mean differential selective effects

Back to article page