Fig. 4

Promoter binding motifs and their location within mammalian HAP1 gene promoters. a The core sequence of each binding site is capitalized, and the most informative positions are indicated in red. Positions given are relative to the translation start site (ATG). The TATA box motifs were identified both as ‘Cellular and viral TATA box elements’ (O$VTATA.01) and ‘muscle TATA boxes’ (O$MTATA.01). b Sequence logos of the binding site motifs. Total height at each position indicates the information content of that position (in bits), and the relative size of each stacked nucleotide indicates its frequency at that position