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Table 2 Summary of epithelial gene expression patterns

From: Tooth and scale morphogenesis in shark: an alternative process to the mammalian enamel knot system

Stage EM LM ED LD
  Scale Tooth Molar Scale Tooth Molar Scale Tooth Molar Scale Tooth Molar
Msx1 - +, +oe - [61] - +, +oe - [61] - + - [61] + +cusp - [61]
Msx2 - +, +oe - [61] + + +ek [61] + + lab +, +oe [61] + +cusp +oe [61]
Msx3 - + n/a + + n/a + + lab n/a + +cusp n/a
Pitx1 + +, +oe + [52] + +, +oe + [52] +root, +oe +, +oe +, +oe [52] -, +oe +, +oe + [52]
Pitx2 - +, +oe + [15] - +, +oe + [15] - -, +oe +, +oe [52] - -, +oe +, +oe [52]
Shh - +tip + [62] + +tip +ek [62] + + tip +ek [62] + +cusp + [63]
Fgf8 - - + [48] +top +tip - [48] +top + tip - [48] - +cusp - [48]
Bmp4 - + - - +lab, +oe +ek +top + +ek +top +lab cusp +ek
+oe [46]   [46] [46] [46]
  1. Summary of gene expression patterns in the epithelial compartment of the catshark scale and tooth buds, in comparison to data published for molar bud development in the mouse. Positive expression in dental epithelium is represented by a +, negative expression by a –, and references for expression in mouse molar buds are cited in the table, except when non available, n/a. Further detail is given when necessary: regionalized expression within the dental epithelium: enamel knot (ek), tip of the tooth bud (tip), top of the scale bud (top), restriction on the lingual (ling) or labial (lab) side of the tooth, cuspid iterative expression (cusp), root of the scale (root) or outer dental epithelium (oe)