Fig. 3

Tex19 protein organization. a MACS schema. Colored cylinders represent conserved regions while “vr” stand for variable regions. Cysteines are depicted as red dots while any other residues, except invariant amino-acids, are shown in black. Gray surfaces represent gaps. Arrows indicate invariant residues and offsets refer to the human sequence, i.e., [RefSeq:NP_997342]. The open green rectangle shows the position of the C₃₄F[AT]C₃₇[FY] motif. Haplorrhini sequences were clustered at the top of the alignment. b C₃₄F[AT]C₃₇[FY] logo. c Secondary structure prediction in conserved “MCP” region (PsiPred), i.e., from residue Met-1 to Trp-54. H and C symbols represent alpha-helix and coil predicted residues, respectively. Confidence value of secondary structure prediction is reported for each residue (maximum confidence equals 9). Invariant cysteines are depicted with a red background while invariant His-27 is shown with a blue background