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Fig. 1 | BMC Evolutionary Biology

Fig. 1

From: Rapid divergence and diversification of mammalian duplicate gene functions

Fig. 1

Evolutionary processes driving the retention of mammalian duplicate genes. a Pie charts depicting the role of each process on different branches of the mammalian phylogeny (yellow = conservation; blue = neofunctionalization of parent copy; pink = neofunctionalization of child copy; black = subfunctionalization; purple = specialization). Numbers of duplicate gene pairs examined along specific branches are indicated beside red tick marks. Additional outgroups (OG) used to date duplicates were lizard (Anolis carolinensis) and fugu (Takifugu rubripes). b Relationship of median K s between pairs of species (human-chimpanzee, human-gorilla, human-orangutan, human-macaque, human-mouse, human-opossum, human-platypus, and human-chicken) to proportions of functionally conserved single-copy (black) and duplicate (red) genes. Least-squares linear regression lines and their slopes are depicted to show rates of decreased functional conservation in single-copy (black) and duplicate (red) genes. *p < 0.05; **p < 0.01; p < 0.001 (see Methods for details)

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