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Table 1 Identified outlier loci in the OXTR gene that are under balancing selection and directionaldirectionalselection using the approaches FDIST, BayeScan and F.LK

From: Signatures of positive selection in the cis-regulatory sequences of the human oxytocin receptor (OXTR) and arginine vasopressin receptor 1a (AVPR1A) genes

  FDIST BayeScan FLK
Locus Function H E F ST P log10(BF) q α i F ST F.LK F.LK.p.val
rs2268494 Intron 3 0.1022 0.0083 0.0000 1.8492 0.0159 −1.3815 0.0291   
rs59190448 Intron 3 0.1825 0.3103 0.0004 3.3977 0.0004 1.447 0.2548 13.521 0.001
rs2268498 Upstream 0.4736 0.0159 0.0009       
rs4643699 Upstream 0.15 0.0081 0.0000       
rs1488467 Upstream 0.1487 0.0081 0.0000       
  1. The results with significance P value < 0.005 are shown for FDIST and F.LK; * the BayeScan log10(BF) > 1.5 indicating ‘very strong’ evidence (P(α ≠ lo = 0.03 → 0.01) for selection. The SNP rs59190448 is under directionalselection and the remaining SNPs under balancing selection