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Table 1 P450 genotype and allele frequencies in a standard laboratory environment

From: The effect of three environmental conditions on the fitness of cytochrome P450 monooxygenase-mediated permethrin resistance in Culex pipiens quinquefasciatus

   Genotype frequency Observed (Expected) Allele Frequency    
Cross Gen. SS RS RR S R na HWEb Driftb
A #1 F2 0.25 0.50 0.25 0.50 0.50    
  F4 0.69 (0.69) 0.28 (0.28) 0.03 (0.03) 0.83 0.17 120 0.9203 <0.0001*
  F5 0.31 (0.38) 0.62 (0.47) 0.07 (0.15) 0.62 0.38 960 <0.0001* <0.0001*
  F6# 0.31 (0.34) 0.55 (0.49) 0.14 (0.17) 0.59 0.41 1040 <0.0001* 0.0105
  F7# 0.24 (0.33) 0.67 (0.49) 0.09 (0.18) 0.58 0.42 1560 <0.0001* 0.2039
  F8 0.19 (0.27) 0.66 (0.50) 0.15 (0.23) 0.52 0.48 900 <0.0001* 0.0004*
  F9# 0.17 (0.24) 0.63 (0.50) 0.20 (0.26) 0.49 0.51 1640 <0.0001* 0.0023
  F10# 0.21 (0.30) 0.68 (0.50) 0.11 (0.20) 0.55 0.45 1760 <0.0001* 1
  F11 0.24 (0.35) 0.70 (0.48) 0.06 (0.17) 0.59 0.41 1520 <0.0001* 0.0009*
  F12 0.47 (0.46) 0.41 (0.43) 0.12 (0.11) 0.68 0.32 400 0.19 0.0002*
A #2 F2 0.25 0.50 0.25 0.50 0.50    
  F4 0.35 (0.43) 0.61 (0.45) 0.04 (0.12) 0.66 0.34 80 0.0018 0.0024
  F5 0.44 (0.46) 0.48 (0.44) 0.08 (0.10) 0.68 0.32 420 0.0349 0.1427
  F6 0.76 (0.77) 0.23 (0.22) 0.01 (0.01) 0.88 0.12 1200 0.0748 <0.0001*
  F7 0.77 (0.77) 0.22 (0.22) 0.01 (0.01) 0.88 0.12 1440 0.1138 0.2772
  F8 0.79 (0.79) 0.20 (0.20) 0.01 (0.01) 0.89 0.11 900 0.5199 <0.0001*
  F9 0.83 (0.83) 0.17 (0.16) 0 (0.01) 0.92 0.08 560 0.0279 0.0252
  F10 0.78 (0.78) 0.21 (0.21) 0.01 (0.01) 0.89 0.11 480 0.4884 <0.0001*
  F11 0.36 (0.36) 0.49 (0.48) 0.15 (0.16) 0.61 0.39 520 0.5651 <0.0001*
  F12 0.38 (0.38) 0.48 (0.48) 0.14 (0.14) 0.62 0.38 240 0.7719 0.3329
B #1 F2 0.25 0.50 0.25 0.50 0.50    
  F4 0.35 (0.44) 0.62 (0.45) 0.03 (0.11) 0.66 0.34 160 <0.0001* <0.0001*
  F5# 0.25 (0.36) 0.70 (0.48) 0.05 (0.16) 0.60 0.40 320 <0.0001* 0.0144
  F6# 0.13 (0.19) 0.61 (0.49) 0.26 (0.32) 0.44 0.56 760 <0.0001* 1
  F7 0.19 (0.29) 0.69 (0.50) 0.12 (0.21) 0.54 0.46 1440 <0.0001* <0.0001*
  F8# 0.22 (0.29) 0.64 (0.50) 0.14 (0.21) 0.54 0.46 800 <0.0001* 0.4023
  F9# 0.13 (0.27) 0.77 (0.50) 0.10 (0.23) 0.52 0.48 1640 <0.0001* 0.0209
  F10# 0.24 (0.35) 0.71 (0.48) 0.05 (0.16) 0.60 0.40 680 <0.0001* 0.1192
  F11 0.73 (0.75) 0.27 (0.23) 0 (0.02) 0.87 0.13 680 <0.0001* <0.0001*
  F12# 0.64 (0.66) 0.35 (0.30) 0.01 (0.04) 0.82 0.18 880 <0.0001* 0.9999
B #2 F2 0.25 0.50 0.25 0.50 0.50    
  F4 0.36 (0.46) 0.63 (0.44) 0.01 (0.10) 0.68 0.32 300 <0.0001* <0.0001*
  F5 0.15 (0.27) 0.74 (0.50) 0.11 (0.23) 0.52 0.48 880 <0.0001* <0.0001*
  F6# 0.30 (0.37) 0.62 (0.48) 0.08 (0.15) 0.61 0.39 1440 <0.0001* 1
  F7 0.18 (0.30) 0.74 (0.50) 0.08 (0.20) 0.55 0.45 1440 <0.0001* <0.0001*
  F8 0.47 (0.50) 0.48 (0.42) 0.05 (0.08) 0.71 0.29 520 0.0002* <0.0001*
  F9 0.38 (0.40) 0.50 (0.47) 0.12 (0.13) 0.63 0.37 920 0.0279 <0.0001*
  F10# 0.50 (0.53) 0.45 (0.40) 0.05 (0.07) 0.73 0.27 1800 <0.0001* 1
  F11 0.67 (0.70) 0.33 (0.28) 0 (0.02) 0.84 0.16 1000 <0.0001* <0.0001*
  F12 0.50 (0.56) 0.50 (0.38) 0 (0.06) 0.75 0.25 1700 <0.0001* <0.0001*
  1. atotal number of 4th instar larvae used in genotype monitoring assay
  2. bNominal p-values are reported for the probability that the data fit the null hypothesis of Hardy-Weinberg equilibrium (or genetic drift)
  3. * indicates tests that remain statistically significant after Bonferonni correction over the entire experiment
  4. # indicates generations that are out of Hardy-Weinberg equilibrium likely due to genetic drift