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Table 2 Tests for selection on the hb anterior activator

From: Statistical tests for natural selection on regulatory regions based on the strength of transcription factor binding sites

N E[ΔS] V[ΔS] Observed average ΔS Case Z P-value Notes
10 -1.61 2.77 -0.31 1 2.48 0.007 Phylogenetic model estimated from hb anterior activator alignment
10 -1.66 2.87 -0.31 1 2.53 0.005 Long time limit distribution of ΔS
7 -1.61 2.77 0.07 1 2.67 0.004 Excluding A3, phylogenetic model estimated from hb anterior activator alignment
5 -1.61 2.77 0.20 1 2.43 0.007 Excluding A3 and substitutions on the lineage leading to the melanogaster group, phylogenetic model estimated from hb anterior activator alignment
5 0 4.26 0.20 2 0.22 0.415 As above, test for adaptive evolution