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Table 1 Duplicability in the transcriptional networks of E. coli and S. cerevisiae

From: Does negative auto-regulation increase gene duplicability?

 

Negative auto-regulation

Positive auto-regulation

Dual auto-regulation

No auto-regulation

E. coli

    

Family size = 1

10

4

2

14

Family size >1

52 (25)

20 (10)

7 (7)

46 (22)

d

0.71

0.71

0.78

0.61

S. cerevisiae

    

Family size = 1

4

5

0

86

Family size >1

0

5

0

26

d

0

0.5

0

0.23

  1. The number of transcription factors belonging to gene families of Family size = 1 (unduplicated) or Family size>1 (duplicated) are given by species and type of auto-regulatory interaction. The number of independent gene families contributing members to the sample is given in parentheses. Duplicability (d) for each regulatory class was determined as d = 1-N(F = 1)/(N(F = 1)+N(F>1)) based on the number of independent families (see Lin et al. 2007). Note that estimates of d can become misleading for low sample sizes so that results should be interpreted with care. No internal comparison is significant at p < 0.05 using Fisher's exact tests.