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Figure 4 | BMC Evolutionary Biology

Figure 4

From: Identifying concerted evolution and gene conversion in mammalian gene pairs lasting over 100 million years

Figure 4

GC content analysis within the gene pairs. Charts compare the GC content of regions evolving in concert with regions evolving divergently. The GC contents at each codon position within gene pairs a) BMP8A/B, b) DDX19A/B and c) TUBG1/2 are shown, along with d) the GC content of introns and 10 kb of upstream and downstream flanking sequence of each gene. GC contents were calculated as an average of five (BMP8A/B) or eight (DDX19A/B and TUBG1/2) multiple sequences (available upon request). Statistical tests (Fisher-Exact test and Yates-corrected Chi-square test) were calculated using the GC content in the human sequences and used to look for significance. P-values less than 0.05 are indicated by *, while P-values less than 0.01 are indicated by **.

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