Figure 7
From: The evolution of core proteins involved in microRNA biogenesis
Phyletic distribution of microRNA biogenesis proteins from this study. Representative species for the taxonomic groups are Homo sapiens (vertebrates), Ciona intestinalis (urochordates), Strongylocentrotus purpuratus (echinoderms), Drosophila melanogaster (arthropods), Caenorhabditis elegans (nematodes), and, Arabidopsis thaliana (plants). Cladogram at the bottom represents relative evolutionary relationships among these groups according to the Tree of Life web project [96]. In italics are a few proteins (Drosha, DGCR8, Pasha HYI1 and DRB4) which were not included in the phylogenetic analyses but are known miRNA or siRNA processing enzymes [2,3].