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Table 1 Parameters of Experimental Evolutions.

From: Experimental evolution and genome sequencing reveal variation in levels of clonal interference in large populations of bacteriophage φX174

  

Per flask: (means)

        

Treatments

anc

Line

N o

N 30

N o /N30

Total hrs

Total flasks

w o

w e

relW

S

relW/w e

Control

1

1.8 × 106

5.7 × 109

0.0003

74.8

147

16.3

20.5

4.1

1.4

0.20

Benign

1

1.6 × 106

6.4 × 109

0.0003

70.8

138

16.3

20.2

3.9

2.1

0.19

Harsh

1

1.0 × 10 7

5.7 × 10 9

0.0014

61.4

66

7.5

10.9

3.4

3.4

0.32

anc 788

           

Control

2

2.3 × 106

3.5 × 109

0.0006

87.4

174

18.0

19.7

1.7

0.8

0.086

 

3

1.3 × 106

4.8 × 109

0.0003

63.5

126

19.1

21.2

2.2

1.1

0.10

Benign

2

3.1 × 106

7.9 × 109

0.0004

38.4

76

17.9

19.8

1.9

1.9

0.097

 

3

3.2 × 106

7.5 × 109

0.0004

43

85

18.5

20.9

2.4

1.3

0.11

Harsh

2

2.4 × 10 7

4.5 × 10 9

0.005

68.5

119

11.3

12.3

1.0

0.5

0.08

 

3

6.3 × 10 7

6.5 × 10 9

0.01

48.3

80

12.2

14.0

1.8

1.0

0.12

  1. Treatment: Control = 2.0 mM CaCl2, Benign = 1.7 mM CaCl2, Harsh = 0.2 mM CaCl2.
  2. N o and N30: Mean phage population sizes at the start and end of each flask growth period.
  3. N o /N30: Bottleneck size; lower numbers indicate lines where beneficial mutations had higher extinction probabilities from bottlenecks.
  4. w o : Mean fitness of the ancestor in treatment conditions (n = 5).
  5. w e : Mean fitness of the endpoint populations in treatment conditions (n = 5).
  6. relW: Mean fitness of the evolved population relative to ancestor (n = 5).
  7. S: Mean selection coefficient; a measure of selection strength.
  8. relW/w e : Fitness change as a proportion of total fitness; a measure of selection strength.
  9. "Harsh" treatments are shown in bold.