Table 2 List of the 19 ICDSs common to M. tuberculosis H37Rv and CDC1551, the ICDSs common to M. tuberculosis H37Rv and M. bovis AF2122/97 and the ICDSs common to M. tuberculosis CDC1551 and M. bovis AF2122/97
M. tub H37Rv | M. tub CDC1551 | M. bovis AF2122/97 | M. tub 210 | M. africanum | Putative function | Functional classification |
|---|---|---|---|---|---|---|
0001 (Rv0095c 136 aa) | 0003 | Mb0098c 260 aa | ICDS | Not Found | Conserved hypothetical | Unknown |
0005 (Rv0325 74 aa – Rv0326 151 aa) | 0010 | Mb0333 229 aa | FL | FL | Hypothetical | Unknown |
0011 (Rv0590 275 aa – Rv0590A 84 aa) | 0016 | Mb0605 343 aa | FL | FL | MCE-family protein | Virulence, detox, adapt |
0013 (Rv0618 231 aa – Rv0619 181 aa) | 0018 | Mb0635 394 aa | ICDS | FL | Galactose-1-phosphate uridylyltransferase | Intermediary metabolism |
0022 (Rv0924c 428 aa – Rv0925c 245 aa) | 0028 | Mb0948c 684 aa | ICDS | ICDS | Manganese transport protein MntH | Cell wall, process |
0031 (Rv1145 303 aa – Rv1146 470 aa) | 0040 | Mb1177 781 aa | FL | FL | Transmembrane transport protein MmpL13 | Cell wall, process |
0037 (Rv1503c 182 aa – Rv1504c 199 aa) | 0048 | Mb1542c 382 aa | ICDS | FL | Conserved hypothetical | Unknown |
0038 (Rv1549 175 aa – Rv1550 571 aa) | 0051 | Mb1576 647 aa | ICDS | FL | Fatty-acid-coA ligase FadD11 | Lipid metabolism |
0039 (Rv1553 247 aa - Rv1554 126 aa) | 0052 | Mb1579 374 aa | ICDS° | ICDS° | Fumarate reductase | Intermediary metabolism |
0045 (Rv1792 59 aa) | 0058 | Mb1820 98 aa | ICDS | FL | ESAT-6-like protein EsxM | Cell wall, process |
0055 (Rv2227 233 aa) | 0072 | Mb2252 124 aa | ICDS | FL | Conserved hypothetical | Unknown |
0066 (Rv2946c 1616 aa – Rv2947 496 aa) | 0084 | Mb2971c 2112 aa | FL | FL | Polyketide synthase Pks15/1 | Lipid metabolism |
0067 (Rv2974c 470 aa – Rv2975c 84 aa) | 0085 | Mb2999c 553 aa | FL | FL | Conserved hypothetical | Unknown |
0072 (Rv3233c 196 aa – Rv3234c 271 aa) | 0092 | Mb3262c 469 aa | FL | FL | Conserved hypothetical | Unknown |
0073 (Rv3337 128 aa – Rv3338 214 aa) | 0094 | Mb3370 297 aa | ICDS | FL | Conserved hypothetical | Unknown |
0078 (Rv3373 213 aa – Rv3374 82 aa) | 0103 | Mb3408 296 aa | ICDS | FL | Enoyl-CoA hydratase EchA18 | Lipid metabolism |
0085 (Rv3725 309 aa) | 0112 | Mb3752 333 aa | FL | FL | Oxidoreductase | Intermediary metabolism |
0086 (Rv3738c 315 aa – Rv3739c 77 aa) | 0113 | Not determined | ICDS | ICDS | PPE family protein | PE/PPE |
0094 (Rv3897c 210 aa – Rv3898c 110 aa) | 0121 | Mb3927c 329 aa | FL | FL | Conserved hypothetical | Unknown |
M. tub H37Rv | M. bovis AF2122/97 | M. tub CDC1551 | M. tub 210 | M. africanum | Putative function | Functional classification |
0118 (Rv3784 326 aa – Rv3785 357 aa) | 0128 | MT3893 712 aa | NT | ICDS | NAD-dependent epimerase/dehydratase | Information pathway |
M. tub CDC1551 | M. bovis AF2122/97 | M. tub H37Rv | M. tub 210 | M. africanum | Putative function | Functional classification |
0057 (MT1806 820 aa – MT1807 94 aa) | 0046 | Rv1759c 914 aa | NT | NT | PE_PGRS family protein | PE/PPE |