Table 1 Eukaryotic β-hexosaminidase proteins belonging to the Glycosyl hydrolase family 20 used in Figure 4.

1

Hex1_At

AAD30612.1

Arabidopsis thaliana

2

Hex2_At

AAM91092.1

Arabidopsis thaliana

3

Hex3_At

BAE99290.1

Arabidopsis thaliana

4

Hex1_Os

BAC83175.1

Oryza sativa

5

Hex2_Os

AAU44085.1

Oryza sativa

6

Hex3_Os

BAD87534.1

Oryza sativa

7

Hex4_Os

BAF11315.1

Oryza sativa

8

Hex5_Os

AAV32135.1

Oryza sativa

9

Hex_Aa

*

Aedes aegypti

10

Hex_Ag

* (HEXO1)

Anopheles gambiae

11

Hex1_Am

XP_624793.1 (HEXO2)

Apis melliphera

12

Hex2_Am

XP_001122538.1 (FDL)

Apis melliphera

13

Hex1_Bm

AAC60521.1 (HEXO1)

Bombyx mori

14

Hex2_Bm

AAT99455.1 (HEXO2)

Bombyx mori

15

Hex_Bman

AAG48701.1

Bombyx mandarina

16

Hex_Cf

AAX94571.1

Choristoneura fumiferana

17

Hex1_Dm

AAF47881.1 (HEXO1)

Drosophila melanogaster

18

Hex2_Dm

AAM48390.1 (HEXO2)

Drosophila melanogaster

19

Hex3_Dm

AAM29423.1 (FDL)

Drosophila melanogaster

20

Hex1_Dp

XP_001352600.1 (HEXO1)

Drosophila pseudoobscura

21

Hex2_Dp

XP_001354979.1 (HEXO2)

Drosophila pseudoobscura

22

Hex3_Dp

XP_001361860.1 (FDL)

Drosophila pseudoobscura

23

Hex_Ms

AAQ97603.1

Manduca sexta

24

Hex_Of

ABI81756.1

Ostrinia furnacalis

25

Hex1_Sf

ABA27427.1

Spodoptera frugiperda

26

Hex2_Sf

ABB76924.1

Spodoptera frugiperda

27

Hex_Tni

AAL82580.1

Trichoplusia ni

28

Hex_Tc

XP_975660.1

Tribolium castaneum

29

Hex_Bt

ABG66991.1

Bos Taurus

30

Hex_Cfa

ENSCAFP00000026129

Canis familiaris

31

Hex_Fc

AAB30707.2

Felis catus

32

Hex1_Hs

AAB00965.1 (HEXA)

Homo sapiens

33

Hex2_Hs

AAA52645.1 (HEXB)

Homo sapiens

34

Hex1_Mf

BAE01310.1

Macaca fascicularis

35

Hex2_Mf

BAE02244.1

Macaca fascicularis

36

Hex1_Mm

ENSMMUP00000014005

Macaca mulatta

37

Hex2_Mm

ENSMMUP00000026294

Macaca mulatta

38

Hex1_Md

ENSMODP00000002170

Monodelphis domestica

39

Hex2_Md

ENSMODP00000002282

Monodelphis domestica

40

Hex1_Mmu

AAC53246.1

Mus musculus

41

Hex2_Mmu

AAA18776.1

Mus musculus

42

Hex_Oa

ENSOANP00000024872

Ornithorhynchus anaticus

43

Hex1_Pt

ENSPTRP00000012396

Pan troglodytes

44

Hex2_Pt

ENSPTRP00000029093

Pan troglodytes

45

Hex_Pp

CAH90623.1

Pongo pygmaeus

46

Hex1_Rn

AAH82097.1

Rattus norvegicus

47

Hex2_Rn

AAH79376.1

Rattus norvegicus

48

Hex_Ss

CAA63123.1

Sus scrofa

49

Hex1_Dr

AAH93192.1

Danio rerio

50

Hex2_Dr

*

Danio rerio

51

Hex_Fr

*

Fugu rubripes

52

Hex_Tn

*

Tetraodon nigroviridis

53

Hex_Xt

*

Xenopus tropicalis

54

Hex_Gg

CAG32597.1

Gallus gallus

55

Hex_Cbr

*

Caenorhabditis briggsae

56

Hex1_Ce

AAA91263.1

Caenorhabditis elegans

57

Hex_Ani

EAA63815.1

Aspergillus nidulans FGSC A4

58

Hex_Aor

BAC41255.1

Aspergillus oryzae

59

Hex_Cal

AAA34346.2

Candida albicans

60

Hex_Cpo

ABB18373.1

Coccidioides posadasii C735

61

Hex_Cba

ABG77528.1

Cordyceps bassiana

62

Hex_Cne

AAW44323.1

Cryptococcus neoformans var. neoformans JEC21

63

Hex_Mgr

XP_365077.1

Magnaporthe grisea 70-15

64

Hex_Man

AAY17951.1

Metarhizium anisopliae

65

Hex_Neo

AAU29327.1

Neotyphodium sp. FCB-2004

66

Hex_Tat

AAT70229.1

Trichoderma atroviride

67

Hex1_Th

AAB47060.1

Trichoderma harzianum

68

Hex2_Th

AAB47061.1

Trichoderma harzianum

69

Hex_Sja

AAW26910.1

Schistosoma japonicum

70

Hex_Fch

ABB86961.1

Fenneropenaeus chinensis

71

Hex1_Ehy

CAE46968.1

Entamoeba histolytica

72

Hex2_Ehy

CAD10500.3

Entamoeba histolytica

73

Hex1_Cin

*

Ciona intestinalis

74

Hex2_Cin

*

Ciona intestinalis

75

Hex_Pma

CAD57204.1

Phallusia mammilata

76

Hex_Ddi

AAA33230.1

Dictyostelium discoideum