Table 1 Definition of technical terms as used in this study
From: The genetic architecture of susceptibility to parasites
additive QTL | Quantitative trait locus; a genetic locus whose alleles differentially affect a quantitative phenotype such as resistance to a parasite. The combined effect of additive QTL is equal to the sum of their individual effects. For the purpose of this study, we do not differentiate between purely additive, dominant and recessive QTL. |
epistatic interaction | A non-additve interaction of genetic loci determining a phenotype, that is the combined effect of different alleles at these loci is different from the sum of the individual loci. |
Interval mapping | Simple interval mapping tests whether an interval between two markers is significantly associated with a QTL. |
Multiple-QTL-model mapping Composite-interval mapping | Both methods combine simple interval mapping with multiple regression. By thus controlling for the effects of other loci, these approaches allow for the accurate detection of multiple QTL defining a trait. |