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Figure 7 | BMC Evolutionary Biology

Figure 7

From: Evolution of the CDKN1C-KCNQ1 imprinted domain

Figure 7

The sequence coverage of repetitive elements in sequences from human, mouse, and tammar. A box plot showing the percent of total sequence masked by SINEs (dark blue), LINEs (light blue), LTR elements (purple), DNA elements (pink), simple repeats (teal), and low complexity regions (pale green) in intron 1, 1b, 9, 10, and 14 of KCNQ1 (A). The percent sequence coverage for each element over the entire region from IGF2-CDKN1C is shown by open circles. There was significantly less sequence masked by LTR and DNA elements in tammar compared to both mouse and human, while there was significantly more sequence occupied by low complexity regions (*). There was significantly less sequence occupied by LINEs in mouse compared to human (**). There was a large range in the sequence covered by LINEs in all species, but particularly in human and mouse. The percent sequence occupied by different types of repetitive elements in the region from IGF2-CDKN1C, in all of KCNQ1, and in introns 9, 10, 1, 1b, and 14 assessed separately (B). The relative percentage of sequence occupied by LINEs is noticeably more than the percentage occupied by LINEs in any other intron from KCNQ1 and this increase was significant for mouse (*). No other significant differences in the relative amounts of sequence covered by different types of elements was seen between regions within species. However, there was also a noticeable increase in the relative amount of simple repeats in intron 9 of tammar compared to other KCNQ1 introns in the tammar.

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