Figure 3

Phylogenetic relationships of metzincin gene families. A. ADAMTS, B. ADAMTS like, C. BMP1/Tolloid-like, D. Meprin and E. TIMP gene families. The trees summarise the phylogenetic analysis. The trees shown were inferred by Neighbor Joining. The values on the tree nodes are Neighbor Joining percentage bootstrap values (black), maximum parsimony bootstrap values (blue) and Bayesian clade credibility values (brown). Nodes also present in the tree generated by Maximum Likelihood are indicated (*). The trees are rooted on the protostome lineage. The scale bars correspond to the number of amino acid replacements per site (horizontal axis). Accession numbers for used in the analyses can be obtained from additional file 1.