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Table 6 Compensation analysis results for the MAP data set.

From: Detecting groups of coevolving positions in a molecule: a clustering approach

PDB

Size

Weight

Stat.

Nmin

p-value

FDR

3D dist.

3D p-value

CYS59, THR99, LYS141, SER231

4

Volume

0.68

147.26

3e-04***

yes

29.66

0.1289

TRP221, ASP227

2

Grantham

0.61

260.63

5e-04***

yes

18.13

0.1688†

LEU20, PRO34, ALA55, ASP90, SER132, VAL157, TRP221, ASP227

8

Polarity

0.75

9.96

8e-04***

yes

38.38

0.1548

GLY122, LEU230

2

Charge

0.49

3.78

9e-04***

yes

7.44

0.002**‡

HIS63, TYR134, GLU180, GLU190, PRO197, ASP242

6

Charge

0.7

3.89

0.0016**

yes

35.58

0.1678

GLN154, GLU158

2

Charge

0.48

4.09

0.0017**

yes

5.96

0.001***‡

PHE105, LYS111

2

Volume

0.47

267.57

0.0031**

yes

20.61

0.2458

VAL24, LYS67, ILE101

3

Volume

0.58

210.55

0.0033**

yes

15.15

0.002**

ASP227, HIS236

2

Charge

0.49

3.15

0.0046**

yes

27.22

0.5255

THR225, GLY244

2

Grantham

0.51

258.01

0.0064**

no

34.16

0.7802

VAL157, THR202

2

Grantham

0.47

310.7

0.0073**

no

18.42

0.1788

ARG19, GLU23, ASN46, VAL50

4

Charge

0.62

5.02

0.0086**

yes

16.04

0.001***

ALA17, ILE153, TRP221, THR222

4

Volume

0.66

126.09

0.0088**

no

26.58

0.0589.†

  1. Legends are the same as in table 5.