From: Detecting groups of coevolving positions in a molecule: a clustering approach
PDB | Size | Weight | Stat. | Nmin | p-value | FDR | 3D dist. | 3D p-value |
---|---|---|---|---|---|---|---|---|
CYS59, THR99, LYS141, SER231 | 4 | Volume | 0.68 | 147.26 | 3e-04*** | yes | 29.66 | 0.1289 |
TRP221, ASP227 | 2 | Grantham | 0.61 | 260.63 | 5e-04*** | yes | 18.13 | 0.1688†|
LEU20, PRO34, ALA55, ASP90, SER132, VAL157, TRP221, ASP227 | 8 | Polarity | 0.75 | 9.96 | 8e-04*** | yes | 38.38 | 0.1548 |
GLY122, LEU230 | 2 | Charge | 0.49 | 3.78 | 9e-04*** | yes | 7.44 | 0.002**‡ |
HIS63, TYR134, GLU180, GLU190, PRO197, ASP242 | 6 | Charge | 0.7 | 3.89 | 0.0016** | yes | 35.58 | 0.1678 |
GLN154, GLU158 | 2 | Charge | 0.48 | 4.09 | 0.0017** | yes | 5.96 | 0.001***‡ |
PHE105, LYS111 | 2 | Volume | 0.47 | 267.57 | 0.0031** | yes | 20.61 | 0.2458 |
VAL24, LYS67, ILE101 | 3 | Volume | 0.58 | 210.55 | 0.0033** | yes | 15.15 | 0.002** |
ASP227, HIS236 | 2 | Charge | 0.49 | 3.15 | 0.0046** | yes | 27.22 | 0.5255 |
THR225, GLY244 | 2 | Grantham | 0.51 | 258.01 | 0.0064** | no | 34.16 | 0.7802 |
VAL157, THR202 | 2 | Grantham | 0.47 | 310.7 | 0.0073** | no | 18.42 | 0.1788 |
ARG19, GLU23, ASN46, VAL50 | 4 | Charge | 0.62 | 5.02 | 0.0086** | yes | 16.04 | 0.001*** |
ALA17, ILE153, TRP221, THR222 | 4 | Volume | 0.66 | 126.09 | 0.0088** | no | 26.58 | 0.0589.†|