From: Detecting groups of coevolving positions in a molecule: a clustering approach
PDB | Size | Weight | Stat. | Nmin | p-value | FDR | 3D dist. | 3D p-value |
---|---|---|---|---|---|---|---|---|
PHE33, LEU69 | 2 | Volume | 1 | 20.99 | 2e-04*** | yes | 16.14 | 0.1339‡ |
PHE33, LEU69 | 2 | Grantham | 1 | 21.99 | 3e-04*** | yes | 16.14 | 0.1339‡ |
PHE33, LEU69 | 2 | Polarity | 1 | 0.3 | 0.0016** | yes | 16.14 | 0.1339‡ |
LEU11, LYS50, TYR103, ARG118 | 4 | Polarity | 0.83 | 5.63 | 0.0014** | yes | 34.22 | 0.5534 |
ALA94, GLY150 | 2 | Polarity | 0.95 | 2.54 | 0.0027** | yes | 8.78 | 0.006**†|
ALA94, GLY150 | 2 | Grantham | 0.93 | 77.72 | 0.0074** | yes | 8.78 | 0.006**†|
PRO37, ALA130 | 2 | Grantham | 0.96 | 94.93 | 0.0034** | yes | 27.81 | 0.6753 |
ALA94, ILE111 | 2 | Volume | 0.87 | 67.97 | 0.0079** | yes | 21.15 | 0.3866†|
THR39, GLY65 | 2 | Volume | 0.98 | 27.63 | 0.0091** | yes | 14.29 | 0.0699.†|
ARG31, SER117 | 2 | Volume | 0.63 | 137.41 | 0.0093** | yes | 11.89 | 0.023*‡ |
ARG31, SER117 | 2 | Grantham | 0.57 | 201.2 | 0.0253* | yes | 11.89 | 0.023*‡ |
LYS42, ASP60, LYS63, THR70 | 4 | Charge | 0.71 | 1.41 | 0.0112* | yes | 20.31 | 0.008** |
GLN26, LYS63, GLU85, TYR103 | 4 | Grantham | 0.76 | 132.11 | 0.0137* | yes | 22.9 | 0.018* |
ASP20, LYS96 | 2 | Charge | 0.6 | 2.23 | 0.0149* | yes | 29.33 | 0.7353†|
THR95, LYS145, GLU148 | 3 | Polarity | 0.63 | 7.42 | 0.0194* | yes | 11.85 | 0.002** |
LEU11, PHE138, GLY150 | 3 | Volume | 0.68 | 41.27 | 0.0333* | yes | 33.1 | 0.6703 |
LYS78, GLU85, ILE99 | 3 | Volume | 0.68 | 37.79 | 0.0373* | yes | 23.37 | 0.1369 |
VAL21, GLN26, ASP27, VAL66, ALA74, LYS78 | 6 | Charge | 0.72 | 1.41 | 0.0415* | no | 24.79 | 0.006** |
LEU9, GLU52, ALA53 | 3 | Polarity | 0.61 | 7.93 | 0.0415* | yes | 33.3 | 0.6993 |
GLN8, LYS42, LYS50 | 3 | Grantham | 0.65 | 117.23 | 0.0455* | no | 38.66 | 0.9171 |
GLY65, LEU76 | 2 | Polarity | 0.95 | 0.89 | 0.0475* | no | 16.46 | 0.1449†|