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Figure 1 | BMC Evolutionary Biology

Figure 1

From: An insight into the phylogenetic history of HOX linked gene families in vertebrates

Figure 1

Gene families with members on at least three of the human HOX-bearing chromsomes 2, 7, 12 and 17. Restricted location of members of many of these gene familes near the HOX clusters suggests that these paralogons may have duplicated simultaneously by block/whole chromosome duplication. SLC4, solute carrier family 4; INHB, inhibins; GLI, glioma-associated oncogene homolog belonging to kruppel family; ITGB, integrin β chains; SP, transcription factor Sp; HOX, homeobox; COL, collagens; MYL, myosin light chains; EGFR/ERBB, epidermal growth factor receptor/erythroblastoma; ZNFN1A, zinc finger protein, subfamily 1A; IGFBP, insulin-like growth factor-binding protein; HH, hedgehog. None of the features of this Figure are drawn to scale.

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