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Table 2 Analysis of markers common to 5 species

From: Recurring genomic breaks in independent lineages support genomic fragility

Fixed species

# blocks

Variable species 1 (# breaks)

Variable species 2 (# breaks)

#joint breaks (β

Avg #joint breaks in shuffles

p-value of correlated break (βp)

hg,mus

126798

canis(127)

rn(421)

3

2.4

0.441

hg,rn

122981

canis(111)

mus(69)

0

0.3

1

canis,mus

121649

hg(81)

rn(416)

0

1.8

1

canis,rn

117204

hg(84)

mus(69)

1

0.3

0.286

hg,mus

126798

gal(1224)

rn(421)

33

19.1

0.002

hg,rn

122981

gal(1152)

mus(69)

6

2.6

0.036

gal,mus

47121

hg(17)

rn(60)

0

0.1

1

gal,rn

46049

hg(19)

mus(19)

1

0

0.01

canis,mus

121649

gal(1253)

rn(416)

35

19.8

0.001

canis,rn

117204

gal(1187)

mus(69)

8

3

0.011

gal,mus

47121

canis(20)

rn(60)

1

0.1

0.126

gal,rn

46049

canis(19)

mus(19)

1

0

0.047

canis,hg

123305

gal(1278)

rn(582)

67

30.5

0

canis,rn

117204

gal(1187)

hg(84)

9

4.4

0.05

gal,hg

38367

canis(17)

rn(55)

0

0

1

gal,rn

46049

canis(19)

hg(19)

3

0

0

canis,hg

123305

gal(1278)

mus(229)

37

12.3

0

canis,mus

121649

gal(1253)

hg(81)

8

4.4

0.081

gal,hg

38367

canis(17)

mus(30)

0

0.1

1

gal,mus

47121

canis(20)

hg(17)

1

0

0.021

  1. For Minimum flank = 2 and Rank differential = 3, the table shows the number of breaks in the variable species, the number of joint breaks, the average number of joint breaks in 1000 random shuffles and the p-value of the joint breaks. This is based on greater than 100 bps markers common to Human, Mouse, Rat, Dog and Chicken. This is based on FBP. In all 20 combinations both variable species have at least 10 breaks and 55% exhibit significant joint breaks.