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Figure 10 | BMC Evolutionary Biology

Figure 10

From: Analysis of transitions at two-fold redundant sites in mammalian genomes. Transition redundant approach-to-equilibrium (TREx) distance metrics

Figure 10

Histogram showing the orthologs of mouse:rat intertaxon pairs using f4 metric, the fraction identical for four fold redundant codon systems (n > 100). While the separation of orthologs from paralogs is larger, the distribution is wider. We do not reject f4 as a dating tool, but only that its use recognizes its particular advantages (broader sample size) and limitations (greater heterogeneity in microscopic rate constants).

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