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Figure 1 | BMC Evolutionary Biology

Figure 1

From: No simple dependence between protein evolution rate and the number of protein-protein interactions: only the most prolific interactors tend to evolve slowly

Figure 1

The relationship between the number of protein-protein interactions for S. cerevisiae proteins and the evolutionary rates between S. cerevisiae and S. pombe orthologs. Shown for each plot is the equation that describes the linear trend line, the r2 value that describes the fraction of the variability in the evolutionary rates that is accounted for by the variability in the number of protein-protein interactions and the p value, which is the probability that the correlation between the number of protein-protein interactions and evolutionary rates could be due to chance. (a) All 1,004 observations. (b) 465 observations that correspond to orthologous protein pairs with ≥ 40% amino acid sequence identity.

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