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Table 2 List of the most abundant domains in each age group

From: Emergence of novel domains in proteins

Domain N PFAM ID
Old   
7 transmembrane receptor (rhodopsin family) 385 PF00001
Protein kinase domain 339 PF00069
Zinc finger, C2H2 type 280 PF00096
PH domain 181 PF00169
Homeobox domain 175 PF00046
RNA recognition motif 139 PF00076
Zinc finger, C3HC4 type 122 PF00097
PDZ domain 120 PF00595
SH3 domain 115 PF00018
Immunoglobulin I-set domain 114 PF07679
Vertebrate   
KRAB box 74 PF01352
SCAN domain 33 PF02023
S-100/ICaBP type calcium binding domain 17 PF01023
Small cytokines (intecrine/chemokine), interleukin-8 like 17 PF00048
Mammalian taste receptor protein 11 PF05296
Protein of unknown function 11 PF04826
u-Par/Ly-6 domain 11 PF00021
Mammalian   
Transcription elongation factor A 4 PF06137
Intracellular adhesion molecule, N-terminal domain 4 PF03921
Cornifin (SPRR) family 3 PF02389
  1. Note that if the domain appeared more than once in the same protein we counted it as one occurrence.