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Figure 7 | BMC Evolutionary Biology

Figure 7

From: Not so pseudo: the evolutionary history of protein phosphatase 1 regulatory subunit 2 and related pseudogenes

Figure 7

Alignment of PPP1R2-related proteins reveals high conservation. An alignment was performed using the protein sequences of PPP1R2P1, PPP1R2P3, PPP1R2P9 and PPP1R2. Black arrows indicate the important phosphorylation sites in PPP1R2 and the respective known kinase. Black boxes encage each PPP1 binding motif known for PPP1R2 and the acidic stretch. Black bars at the bottom of each row of alignment show the region covered by the peptides obtained. Two-headed arrow indicates the peptide for which the antibody used for immunoprecipitation was raised. * represent high conservation, : and . represent low conservation in which the substituted residue has respectively more or less similar properties.

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