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Figure 3 | BMC Evolutionary Biology

Figure 3

From: Endosymbiosis in trypanosomatids: the genomic cooperation between bacterium and host in the synthesis of essential amino acids is heavily influenced by multiple horizontal gene transfers

Figure 3

Threonine synthesis pathway. Enzymes surrounded by a thick gray box were shown to be horizontally transferred from Bacteria (see main text). Metabolites – I: glycine; II: threonine; III: phosphohomoserine; IV: homoserine; V: aspartate 4-semialdehyde; VI: 4-aspartyl-phosphate; VII: L-aspartate. Enzymes – 4.1.2.5: threonine aldolase; 2.7.2.4: aspartate kinase; 1.2.1.11: aspartate-semialdehyde dehydrogenase; 1.1.1.3: homoserine dehydrogenase; 2.7.1.39: homoserine kinase; 4.2.3.1: threonine synthase. Abbreviations as for Figure 1.

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