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Table 3 DAVID gene ontology functional annotation enrichment analysis in magnetic simulators

From: Suboptimal evolutionary novel environments promote singular altered gravity responses of transcriptome during Drosophilametamorphosis

GBF ΔT ↓O2 G level Affected genes (limma raw(FDR)) Behaviour responses Metamorphosis/morphogenesis/organogenesis Stress responses GO clusters observed also in control conditions
  Reproductive/ mating/oviposition Sensorial/ hormonal/ odorant prot.   Abiotic (heat, light & hypoxia) Biotic (defense & immune sys.) Insect cuticle proteins Cytoesqueleton and cell adhesion Proteolysis Red-Ox states/energy Hemo/ metals/ions binding
Mag No Yes 0g* UP 61(0)    4.5×10-2     3.8×10-2    
    0g* Down 62(0) 1.7×10-19        6.2×10 -4   
    1g* UP 17(0)           
    1g* Down 25(0)         3.4×10-2   
    2g* UP 420(30) 6.4×10-2 8.8×10-3 2.1×10 -4 1.3×10-2 1×10-2 5×10-8 6.7×10 -4    3.1×10-3
    2g* Down 328(42) 6.1×10-22 1.2×10 -5    6.6×10-2    4.4×10 -6 2.9×10-8  
  Yes Yes 0g* UP 635(458) 1.9×10 -4 7.7×10 -5   1.9×10-3 2.7×10-2    1.1×10 -5 4.2×10-12 1.7×10 -6
    0g* Down 524(349) 2×10-2 2.3×10-3   3.4×10-2 1.5×10-2 2×10-25   2.9×10-3 7.2×10-11 4.7×10 -5
    1g* UP 350(196)   2.9×10-3   1×10-3 1.4×10-3    1.1×10-2 1.1×10-11 2.9×10-8
    1g* Down 191(97)       2.5×10-18   2.7×10-2   
    2g* UP 208(7)      1.4×10-2     1.2×10-6 8.6×10 -5
    2g* Down 157(2)       2.3×10-15   6.8×10-2   
  1. The number of up- or down-regulated probesets in each GBF facility (first column) and condition (column 2 to 4) has been calculated and is shown in the fifth column (filtering with a p-value limma < 0.001). Relative enrichment analysis of these gene lists have been done, and the more frequent GO groups observed in experimental (columns 6 to 10), or 1g/environmental controls (columns 11 to 15) are included. Statistically meaningful p values are indicated in the table using italics and bold fonts to emphasize a greater level of enrichment in each particular GO group is observed. * indicates the presence of a high magnetic field.