Molecular evolution of Drosophila Sex-lethal and related sex determining genes

Table 1 Significant likelihood ratio tests of selection on Sxl in Drosophila, the Tephritidae and M. domestica sequences

Test	Line	Alternative M^a	Null M^a	2ΔL	df	P^b	Sites^c
1	a	Nearly Neutral	One ratio	112.53	1	< 0.0001	21
2-D	b	Local selection	Local relaxation	9.16	1	0.0024	17
2-T	c	Local relaxation	Uniform Selection	262.18	2	< 0.0001	1
2-T	d	Local selection	Local relaxation	5.46	1	0.019	0
3-D	e	Local relaxation	Uniform Selection	248.25	2	< 0.0001	0
3-R^d	f	Local relaxation	Uniform Selection	208.30	2	< 0.0001	43

^aAlternative and null models, see Additional File 2, Table S1 for more information on models and Log-likelihood values, ^bP value calculated from a χ²distribution, ^cnumber of sites significant in Bayesian post-hoc tests (P < 0.05), ^dclade consisting of all species excluding Drosophila. The alignment, after deleting gaps, was composed of 298 codons. Tests that we deemed weakly significant because Bayesian post-hoc tests did not detect relevant AA are shown in italics.

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