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Table 4 The average rates of nonsynonymous (d N ) and synonymous substitutions (d S ) per

From: Evolution of major histocompatibility complex class I and class II genes in the brown bear

   dN dS Z P
MHC class I All sites 15.1 (2.6) 13.7 (2.8) 0.439 0.331
  ABS 50.6 (11.5) 26.2 (11.1) 1.627 0.053
  non-ABS 10.1 (2.3) 12.0 (3.0) −0.594 1.000
MHC class II DRB All sites 10.2 (2.4) 2.6 (1.2) 3.792 0.000
  ABS 42.2 (9.4) 8.3 (4.4) 4.320 0.000
  non-ABS 2.9 (1.1) 1.1 (1.1) 1.536 0.064
MHC class II DQA All sites 3.3 (1.7) 2.3 (2.4) 0.327 0.372
  ABS 12.5 (6.7) 10.2 (13.5) 0.144 0.433
  non-ABS 0.0 0.0 0.000 1.000
MHC class II DQB All sites 6.5 (1.9) 6.3 (2.5) 0.071 0.472
  ABS 20.9 (6.8) 7.6 (5.8) 1.967 0.026
  non-ABS 2.0 (1.1) 6.1 (3.0) −1.197 1.000
  1. Distances and standard error values are given as percentages per site; standard errors obtained through 1000 bootstrap replicates in parentheses. Significant results are highlighted in bold.