Genome-wide DNA methylation analyses in the brain reveal four differentially methylated regions between humans and non-human primates

Table 3 Validation of DMRs in additional independent samples

DMR ID	Gene	H4	H5	M4	M5	M6	M7	Differences	P value	Corrected P value^a	P value (all)^b
103	K6IRS2	0.289	0.252	0.936	0.852	0.902	0.958	−0.641	6.22E-05	1.9E-04	1.7E-08
143	RNF32	0.403	0.427	0.930	0.875	0.925	NA^c	−0.495	2.6E-04	7.8E-04	2.3E-08
8	ICAM1	0.103	0.200	0.455	0.520	0.410	0.500	−0.320	2.5E-03	7.5E-03	9.7E-08

^athe P values after Bonferroni correction by 3 tests.
^bthe nominal P values obtained using all the samples including both MeDIP-Chip samples and additional independent samples.
^cnot available.

ISSN: 2730-7182