Figure 1

Protein family and protein domain change indices. At each lineage, the index for protein family change is followed by that of domain change (separated by back slash ‘/’). The index for protein family change was calculated using the log ratio of protein family birth and death events reconstructed from 17,752 homologous multimember families (151,044 proteins), thus representing how changes in protein families at any given lineage favor family gain or family loss. The index defining the change in protein domain complexity was calculated using the log ratio of protein domain birth and death events reconstructed from 123,084 proteins (5,106 domains). Analogous to protein family change, this represents how domain changes at any given lineage favor domain gain or loss.