BMC Ecology and Evolution

Table 1 McDonald-Kreitman (MK) tests and genetic divergence

From: Molecular evolution of a gene cluster of serine proteases expressed in the Anopheles gambiae female reproductive tract

	AGAP005194						AGAP005195						AGAP005196
	Fixed		Polym.				Fixed		Polym.				Fixed		Polym.
	S	NS	S	NS	p	Dxy	S	NS	S	NS	p	Dxy	S	NS	S	NS	p	Dxy
ga-ar	0	0	26	29	n.s.	0.027	0	0	15	22	n.s.	0.010	0	0	18	29	n.s.	0.023
ga-qd	0	0	26	35	n.s.	0.049	0	0	15	24	n.s.	0.017	0	0	16	25	n.s.	0.019
ga-ml	0	0	25	24	n.s.	0.022	8	13	15	21	1.000	0.046	0	8	15	17	0.016 ^*	0.037
ga-mr	1	2	26	35	1.000	0.059	9	22	13	24	0.615	0.067	4	5	14	15	1.000	0.038
ar-qd	1	0	19	36	0.357	0.049	1	1	6	10	1.000	0.014	0	0	11	25	n.s.	0.026
ar-ml	0	0	14	23	n.s.	0.022	8	13	4	5	1.000	0.039	0	0	10	24	n.s.	0.035
ar-mr	1	2	17	35	1.000	0.058	9	23	2	8	0.705	0.060	4	2	9	21	0.161	0.044
qd-ml	1	0	17	29	0.383	0.046	8	14	6	7	0.724	0.046	0	0	7	18	n.s.	0.030
qd-mr	2	2	17	35	0.598	0.059	8	23	4	10	1.000	0.064	4	2	6	16	0.147	0.030
ml-mr	1	2	15	28	1.000	0.053	7	15	2	5	1.000	0.040	5	4	1	4	0.301	0.023

S = synonymous sites, NS = nonsynonymous sites; p-values computed by Fisher's exact test; * significant p-value
(< 0.05) for MK test; ga = A. gambiae, ar = A. arabiensis, qd = A. quadriannulatus, ml = A. melas, mr = A. merus

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