N
|
c
|
d
|
Sample size
|
Mean t0.25,control
|
Mean t0.25,plast
|
p-value
|
---|
8
|
0.4
|
0.125
|
498
|
27.55
|
46.72
|
< 2.2 × 10-16
|
| |
0.25
|
498
|
30.69
|
45.91
|
< 2.2 × 10-16
|
| |
0.5
|
497
|
28.01
|
45.63
|
< 2.2 × 10-16
|
|
0.3
|
0.125
|
495
|
18.8
|
26.49
|
< 2.2 × 10-16
|
| |
0.25
|
498
|
19.25
|
25.86
|
< 2.2 × 10-16
|
| |
0.5
|
498
|
26.44
|
25.99
|
< 2.2 × 10-16
|
16
|
0.25
|
0.125
|
413
|
41.61
|
106.96
|
6.9 × 10-14
|
| |
0.25
|
431
|
35.66
|
138.98
|
< 2.2 × 10-16
|
| |
0.5
|
418
|
49.76
|
162.98
|
< 2.2 × 10-16
|
|
0.2
|
0.125
|
462
|
43.4
|
143.45
|
< 2.2 × 10-16
|
| |
0.25
|
466
|
36.48
|
133.72
|
< 2.2 × 10-16
|
| |
0.5
|
471
|
42.01
|
120.97
|
< 2.2 × 10-16
|
20
|
0.2
|
0.25
|
152
|
35.45
|
103.8
|
4.4 × 10-10
|
- The number of generations that a population needs to increase the fraction of its circuits in the new genotype network to 25 percent is significantly higher with plasticity, i.e., t0.25,plast>t0.25,controlaccording to a Wilcoxon signed-rank test.
- The value of d is that of the old genotype network. We analyzed 500 pairs of evolving populations for each combination of N, c and d. We discarded population pairs in which any of the populations never had 25% of its circuits in the new genotype network by the end of the simulation (t = 104). Thus, our actual sample size was lower than 500 populations. The probability α of gene-activity perturbation in s0 equaled 0.05 per gene when N = 8, 0.025 when N = 16, and 0.02 when N = 20. Population size M = 1000; μ = 0.5; ωnative = 0.5.