Skip to main content

Table 1 Gene conversion analysis for the TLR1 gene family using coding sequences from birds and mammals

From: Molecular evolution of the vertebrate TLR1 gene family - a complex history of gene duplication, gene conversion, positive selection and co-evolution

Group

Sequence names

BC KA P-value

N

Central

C

Number of Polymorphisms

Number of Differences

Total Differences

Avian TLR1A/B

GgalTLR1A:GgalTLR1B

3.61E-51

1-1177

--

1178-2374

301

16

415

 

MgalTLR1A:MgalTLR1B

2.46E-50

1-1177

--

1178-2387

307

26

411

 

AplaTLR1A:AplaTLR1B

1.47E-43

1-1190

--

1191-2397

308

38

432

 

TgutTLR1A:TgutTLR1B

3.20E-60

1-1186

--

1187-2466

335

1

354

Avian TLR2A/B

GgalTLR2A:GgalTLR2B

3.16E-40

63-713

714-1290

1291-2375

418

2

287

 

MgalTLR2A:MgalTLR2B

3.62E-33

47-713

714-1328

1329-2385

428

7

275

 

AplaTLR2A:AplaTLR2B

2.36E-37

34-725

726-1284

1285-2371

445

22

294

 

TgutTLR2A:TgutTLR2B

4.24E-39

42-718

719-1284

1285-2328

420

14

296

Mammalian TLR1/6

HsapTLR1;HsapTLR6

1.75E-32

1-1315

--

1316-1960

303

13

529

 

PtroTLR1;PtroTLR6

9.80E-34

1-1315

--

1316-2235

405

35

525

 

PpygTLR1;PpygTLR6

2.15E-32

1-1323

--

1324-2235

403

33

514

 

CjacTLR1;CjacTLR6

2.45E-36

1-1315

--

1316-2231

402

21

504

 

MmulTLR1;MmulTLR6

5.10E-38

1-1315

--

1316-2202

391

22

520

 

RnorTLR1;RnorTLR6

1.12E-66

1-1332

--

1334-2225

391

5

590

 

MmusTLR1;MmusTLR6

4.09E-62

1-1311

--

1312-2230

402

12

585

 

BtauTLR1;BtauTLR6

1.30E-38

1-1332

--

1333-2403

475

16

473

 

SscrTLR1;SscrTLR6

2.48E-37

1-1308

--

1309-2340

460

29

495

 

EcabTLR1;EcabTLR6

8.00E-27

1-1315

--

1316-2234

404

48

529

 

CfamTLR1;CfamTLR6

9.51E-40

1-1315

--

1316-2235

405

16

506

 

EeurTLR1;EeurTLR6

1.91E-52

1-1308

--

1309-2235

407

14

550

  1. The boundaries of gene converted regions were based on GENECONV analysis with mismatches allowed (/g1 = 1). The avian species are chicken, turkey, duck and zebra finch and the mammalian species are cattle, dog, marmoset, horse, hedgehog, human, rhesus monkey, mouse, orangutan, chimpanzee, rat and pig. The positions of fragments are given with respect to the aligned sequences of avian TLR1A/B, avian TLR2A/B or mammalian TLR1/6. The gene-converted fragments of the TLR1 gene family members are the C-terminal regions of avian TLR1A/B, avian TLR2A/B, mammalian TLR1/6, and the N-terminal regions of avian TLR2A/B. "BC KA p-values": Bonferroni-corrected KA (BLAST-like) P values. "Number of Polymorphisms", "Number of Differences" and "Total Differences" represents the number of polymorphic sites within gene-converted fragments of each group, number of mismatched sites between gene-converted paralogous fragments from the same species and total number of mismatched sites between aligned paralogous sequences from the same species, respectively.