Skip to main content
Figure 1 | BMC Evolutionary Biology

Figure 1

From: Protein engineering of conger eel galectins by tracing of molecular evolution using probable ancestral mutants

Figure 1

Structure and mutants of Con-anc. (A) 3D structure of Con-anc with liganded lactose, which was predicted by homology modeling, based on congerin I. The amino acid residues in N- and C-termini (NT and CT, respectively) and loops 3, 5, and 6 (L3, L5, and L6, respectively) of Con-anc mutants are represented by the space-filling model. (B) Aligned amino acid sequences of ConI, ConII, Con-anc, and Con-anc mutants. The sequences were aligned using the ClustalW program. Residue numbers of ConI were used as reference for all the congerins and mutants in this study. Positions of the strands (S1--S6, F1--F5) and loops (L1--L10) are indicated by thick and thin horizontal lines, respectively. The mutated amino acid positions are boxed in color.

Back to article page