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Table 3 Summary of the results of the site-specific analysis: in each case the most significant model was M8

From: Positive selection neighboring functionally essential sites and disease-implicated regions of mammalian reproductive proteins

Gene

n

Parameter estimates

# Positively selected Sites

Adam2

12

p0 = 0.92632 p = 0.37637

q = 0.60688

p1 = 0.07368 ω = 3.94326

45>0.50

15>0.95

5>0.99

Catsper1_Exon1 (primates only)

16

p0 = 0.82736 p = 0.13661

q = 0.03850

p1 = 0.17264 ω = 3.13071

95>0.50

7>0.95

1>0.99

Catsper1_Mammals

(non-primate mammals only)

8

p0 = 0.83315 p = 0.34233

q = 0.51278

p1 = 0.16685 ω = 3.26879

124>0.50

30>0.95

8>0.99

Col1a1

10

p0 = 0.98023 p = 0.04796

q = 0.32286

p1 = 0.01977 ω = 4.09285

66>0.50

21>0.95

8>0.99

Ph20

11

p0 = 0.87658 p = 0.56141

q = 0.83349

p1 = 0.12342 ω = 2.20500

39>0.50

3>0.95

0>0.99

Porimin

10

p0 = 0.85067 p = 0.41864

q = 0.32952

p1 = 0.14933 ω = 12.21841

30>0.50

13>0.95

5>0.99

Prkar2a

17

p0 = 0.95102 p = 0.16339

q = 0.98823

p1 = 0.04898 ω = 2.60992

19>0.50

4>0.95

0>0.99

Semg2

12

p0 = 0.97236 p = 0.01163

q = 0.00500

p1 = 0.02764 ω = 12.26405

41>0.50

5>0.95

2>0.99

Sp56

14

p0 = 0.98807 p = 0.16114

q = 1.12262

p1 = 0.01193 ω = 3.81710

8>0.50

2>0.95

2>0.99

Zp2

18

p0 = 0.87339 p = 0.63945

q = 0.75356

p1 = 0.12661 ω = 2.04655

52>0.50

9>0.95

6>0.99

Zp3

13

p0 = 0.91489 p = 0.30029

q = 0.77328

p1 = 0.08511 ω = 1.92305

48>0.50

0>0.95

0>0.99

  1. Following LRT analysis M8 was chosen in each case as the most significant model. n refers to the number of taxa in each dataset. The proportion of sites (p), evolving under each corresponding selective pressures (ω) are shown. For example, p0 refers to the proportion of the protein evolving under the selective pressure value given by ω0. The parameters p and q describe the beta distribution. The final column gives the number of sites with posterior probability (PP) of 0.50, 0.95 and 0.99 that belong in the positively selected category or sites. The number before the ">" refers to the number of sites with a specific PP value.