Table 4 Degrees and duplicabilities of the genes in the malaria parasite PIN belonging to each functional category
GO biological process category | Mean degreea | Mean duplicabilitya | # of proteinsa |
|---|---|---|---|
Pathogenesis | 5.6 | 2.21 | 42 |
Interaction with host | 5.0 | 2.15 | 42 |
Multi-organism process | 5.0 | 1.18 | 93 |
Proteolysis | 4.9 | 0.99 | 20 |
Cellular catabolic process | 4.8 | 0.09 | 19 |
Symbiosis encompassing mutualism through parasitism | 4.6 | 1.27 | 86 |
Ubiquitin-dependent protein catabolic process | 4.4 | 0.07 | 25 |
Cellular component assembly | 4.3 | 0.59 | 22 |
Biological adhesion | 4.3 | 1.10 | 26 |
Localization | 4.2 | 0.10 | 13 |
Translation | 4.1 | 0.16 (-) | 115 |
Gene expression | 4.0 | 0.26 | 294 |
Cellular macromolecule catabolic process | 4.0 | 0.08 | 26 |
RNA metabolic process | 3.9 | 0.31 | 159 |
Macromolecule catabolic process | 3.8 | 0.07 | 29 |
Protein catabolic process | 3.8 | 0.07 | 26 |
Biosynthetic process | 3.7 | 0.21 | 127 |
Biopolymer catabolic process | 3.7 | 0.06 | 25 |
Response to stimulus | 3.5 | 0.15 | 28 |
Nucleobase, nucleoside, nucleotide and nucleic acids metabolism | 3.4 (--a) | 0.28 | 147 |
Ribonucleoprotein complex biogenesis and assembly | 3.4 | 0.19 | 20 |
Post-translational protein modification | 3.1 | 1.33 | 8 |
Antigenic variation | 3.1 | 0.38 | 38 |
Cellular component organization | 3.1 | 0.24 | 26 |
Transport | 2.1 | 0.16 | 8 |
All proteins in the malaria parasite PIN | 4.3 | 0.42 | 1,267 |