Skip to main content

Table 2 Biacore analysis of BALB and CAST IL4 binding to IL4Rα

From: Diversifying selection and functional analysis of interleukin-4 suggests antagonism-driven evolution at receptor-binding interfaces

 

ka(1/Ms)

kd(1/s)

KA(1/M)

KD(M)

BALB IL4

2.49E+06

5.18E-04

4.79E+09

2.09E-10

CAST IL4

3.16E+06

7.13E-04

4.44E+09

2.26E-10

  1. Data are the average of two independent experiments performed with two independently coupled chips.
  2. ka is the association rate constant (M-1s-1);
  3. kd - is the dissociation rate constant (s-1);
  4. KA - is the equilibrium binding (affinity) constant (ka/kd) (1/M);
  5. KD - is the equilibrium dissociation constant (kd/ka) (M)
Back to article page

BMC Ecology and Evolution

ISSN: 2730-7182

Contact us