Figure 6
From: Conservation and divergence of ADAM family proteins in the Xenopus genome
The truncated propeptide of X. tropicalis ADAM11 as a result of different exon usage. A) Sequence alignment of human, mouse, X. tropicalis and zebrafish ADAM11 was generated using ClustalX. Only the N-terminal signal peptide and propeptide are shown; arrow points to predicted signal peptide cleavage sites. See Additional File 5 for complete sequence alignment. B) Comparison of exon-intron structures in the signal (S) and propeptide (PRO) encoding regions of human and X. tropicalis adam11 transcript. Open boxes represent exons conserved in both species, and filled boxes represent exons in human adam11 that are completely or partially absent in X. tropicalis adam11.