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Table 3 Virulence of analysed Trichomonas vaginalis strains assessed on the basis of clinical findings, histopathological examination of ectocervical biopsies and results of mouse assays after intraperitoneal and subcutaneous inoculation.

From: Concordance between genetic relatedness and phenotypic similarities of Trichomonas vaginalis strains

 

Intraperitoneal mouse test

Subcutaneous mouse test

Patients(d)

Strain

Mortality % (a)

Virulence index (b)

N

Abscess volume (mm3) (c)

N

Symptoms

Histopathology

TV 85–08

50

7.7

20

132

38

2

2

TV 73–87

43

10.4

30

66

31

2

2

TV 71–96

24

6.0

37

121

38

2

3

TV 79–49

73

10.7

30

176

65

1

1

TV 14–85

86

10.8

30

127

29

4

3

TV 67–77

47

8.7

30

63

40

2

2

TV 10–02

0

3.7

20

79

37

1

1

TV 7–37

90

13.4

30

230

41

4

4

FF28

75

7.6

12

117

28

0

nd

JH-31A

nd

nd

nd

78.6

49

0

0

TV 17–48

83

11.1

30

183

58

4

4

  1. (a) Percent of inoculated mice that died within three weeks after inoculation. (b) Virulence index of Cavier et al.[23] ranges from 0 (avirulent) to 16 (maximum virulence). (c) Mean volumes of subcutaneous abscesses developed six days after inoculation. (d) Clinical and pathological changes found at gynaecological and histopathological examination rated according to increasing severity from 1 to 4 as indicated in reference [2].